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Progesterone is also an intermediate compound in the biochemical pathways that lead to the production of other important hormones such as testosterone, estrogen and cortisol. Testosterone plays a role in maintaining both the male and female sex drive, and also helps maintain strong bones and energy levels. Estrogen plays a key role in the development of female sexual characteristics and in the menstrual cycle. buy perimenopause help In post-menopausal women, estrogen decreases bone reabsorption, reverses atrophy of the vulva and vagina, and exerts a protective effect against cardiovascular disease. Cortisol plays a role in glucose metabolism, provides increased energy during periods of stress, and has an anti-inflammatory action.