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But if you cannot find relief tension or stress headache everyday in lifestyle changes, there are prescription medications which a physician can prescribe for you. Midrin is often prescribed for tension headaches which combines the pain reliever acetaminophen with a mild sedative that helps you relax and release the tension. There are problems with Midrin, though. It should not be overused, or else it could cause severe, irreversible liver damage. The sedative within Midrin can also be addictive. Consult your doctor before taking Midrin or any other drug to manage your tension headaches. While tension headache symptoms are extremely annoying and unpleasant, they can be controlled with lifestyle changes.